The store will be located in the former Downtown Duty Free site, and will officially open on 28 February.
The store's wares will focus on DVDs, CDs, games, computers, IT equipment, cameras and navigation, and will incorporate two special areas designated to Apple and Telstra stock.
JB Hi-Fi says the new store location is a lucky win for the retailer, and will take some of the pressure of the existing store underneath the Queen Victoria Building.
"We are excited to have secured such a prominent location, our existing store in the CBD has been overtrading for quite some time and with Brazin closing the HMV Pit St Mall store we saw an opportunity to increase our market share as well as introduce to the city a substantial technology offering," said JB Hi-FO CEO, Richard Uechtritz.